MTE4596 - Biomaterials 2 - Monash University

Overview

Biocompatibility is explored and is related to the foreign body response. The importance of the interfacial properties of biomaterials is covered and includes factors affecting cellular response and protein adsorption. Polymers and ceramics used in medicine are reviewed with examples including the total hip joint replacement (TFJR), heart valves, catheters and vascular grafts and hydrogels used in ophthalmology. Drug delivery devices are reviewed and include degradation mechanisms and kinetics. Biomaterials with biological recognition and smart biomaterials will be studied. Biosensors and examples in bionanotechnology will be investigated. Tissue engineering and scaffold manufacture are covered and the use of stem cells for regenerative medicine reviewed.

Offerings

S2-01-CLAYTON-ON-CAMPUS

Requisites

Prohibition

Rules

Enrolment Rule

Contacts

Chief Examiner(s)

Matt Moore

Unit Coordinator(s)

Matt Moore

Learning outcomes

On successful completion of this unit, you should be able to:

Have a basic understanding of the processes involved in the foreign body response and biocompatibility

Appreciate some factors that affect protein adsorption

Understand the different classes of polymeric biomaterials used in the body.

Be familiar with some of the degradation processes of polymers

Describe some methods of drug delivery

Describe the action and use of smart materials

Be familiar with ceramic materials used in body and some aspects of thermal spraying

Understand some techniques used in tissue engineering including some methods of scaffold manufacture

Understand some techniques commonly used to characterise biomaterial surfaces.

10.

Be able to review a journal article and provide a detailed assessment.

11.

Have an ability to communicate within a team, and submit a group assignment.

Teaching approach

Active learning

The teaching of this unit involves a combination of pre-class reading and preparation, expert-led sessions comprising teaching session material and active learning activities. Teaching is also carried out in practice classes. The list of reading and preparatory material will be provided several days before each session. Preparation work will need to be completed before the start of each week's session.

Assessment summary

Continuous assessment: 50%

Final assessment: 50%

This unit contains threshold hurdle requirements that you must achieve to be able to pass the unit. You are required to achieve at least 45% in the total continuous assessment component and at least 45% in the final assessment component. The consequence of not achieving a hurdle requirement is a fail grade (NH) and a maximum mark of 45 for the unit.

Assessment

1 - Test(s)

2 - Assignment(s)

3 - Practical activities and related work

4 - Final assessment

Scheduled and non-scheduled teaching activities

Assessments

Laboratories

Practical activities

Workshops

Workload requirements

Workload

The minimum total expected workload to achieve the learning outcomes for this unit is 144 hours per semester typically comprising a mixture of 3-6 hours of scheduled learning activities and 6-8 hours of independent study per week. Scheduled activities may include a combination of teacher-directed learning, peer-directed learning and online engagement. Independent study may include associated readings, assessment and preparation for scheduled activities.

Other unit costs

The following items are mandatory for practical aspects of the unit and should be purchased at your own cost as you will be reusing them throughout your course.

Calculator
Protective clothing and equipment:
- Laboratory coat (Approximately AUD35 to AUD55)
- Safety glasses (Approximately AUD8)
- Laboratory-appropriate enclosed footwear (Non-porous material, equipped with non-absorbent, slip-resistant soles)

Costs are indicative only.

Availability in areas of study

E6011 Master of Professional Engineering - Specialisation: Materials engineering
Minor: Medical technology