CHE3171 - Bioprocess technology

Overview

This unit explores how scalable, commercially viable process-unit operations are harnessed by the biotechnology industry for the production of valuable biomolecules (eg recombinant proteins, peptides, vaccines, enzymes, and nucleic acids). The design, operation and economic issues surrounding large-scale biomolecular process equipment including bioreactors, filtration systems, chromatographic columns, sterilisation and aseptic … For more content click the Read More button below.

This unit explores how scalable, commercially viable process-unit operations are harnessed by the biotechnology industry for the production of valuable biomolecules (eg recombinant proteins, peptides, vaccines, enzymes, and nucleic acids). The design, operation and economic issues surrounding large-scale biomolecular process equipment including bioreactors, filtration systems, chromatographic columns, sterilisation and aseptic operation, auxiliary equipment and the associated control systems will be considered. The wider biotechnology environment will be considered especially with regards to GxP, national and international regulatory bodies, biosafety and commercialisation.

Offerings

S2-01-MALAYSIA-ON-CAMPUS

Requisites

Prerequisite

Contacts

Chief Examiner(s)

Dr Song Cher Pin

Unit Coordinator(s)

Dr Song Cher Pin

Learning outcomes

On successful completion of this unit, you should be able to:

Describe biological systems and molecules and how these are harnessed in biotechnology.

Analyse the performance of unit operations involved in bioprocessing.

Generate a process flow diagram for a bioprocessing plant.

Teaching approach

Active learning

Assessment summary

Continuous assessment: 50%

Final assessment: 50%

This unit contains hurdle requirements that you must achieve to be able to pass the unit. You are required to achieve at least 45% in the total continuous assessment component and at least 45% in the final assessment component. The consequence of not achieving a hurdle requirement is a fail grade (NH) and a maximum mark of 45 for the unit.

Assessment

1 - Assignments

2 - Tests

3 - Final assessment

Scheduled and non-scheduled teaching activities

Laboratories

Practical activities

Workshops

Workload requirements

Workload

The minimum total expected workload to achieve the learning outcomes for this unit is 144 hours per semester typically comprising a mixture of 3-6 hours of scheduled learning activities and 6-9 hours of independent study per week. Scheduled activities may include a combination of teacher-directed learning, peer-directed learning and online engagement. Independent study may include associated readings, assessment and preparation for scheduled activities.

Other unit costs

The following item is mandatory for practical aspects of the unit and should be purchased at your own cost as you will be reusing them throughout your course.

Calculator

Protective clothing and equipment:
• Laboratory coat - approximately $35 to $50
• Safety glasses - approximately $8, or prescription safety glasses (if required) - approximately $350
• Laboratory-appropriate enclosed footwear (non-porous material, equipped with non-absorbent, slip-resistant soles)

Costs are indicative only.