BCH3052 - Protein biology: From sequence to structure and disease

Overview

The course will give you an advanced understanding of protein structure-function in the context of human disease. Major themes relate the various levels of protein structure to their wide ranging functions, introduce modern techniques used in the analysis of structure and function, and explore the rapidly developing area of protein-related biotechnologies and drug design. Topics to be covered include examples of aberrations in protein structure that lead to alteration in function in a variety of biological contexts, emphasizing disease. Additionally the use of bioinformatics in aiding our understanding of protein sequence, structure and function will be highlighted.

Offerings

S2-01-CLAYTON-ON-CAMPUS

Rules

Enrolment Rule

Contacts

Chief Examiner(s)

Prof Mibel Aguilar

Unit Coordinator(s)

Professor Martin Stone

Teaching approach

Active learning

Learning activities in this unit will consist of:

A weekly online lesson (readings, videos, formative interactive exercises with feedback) introducing the theory behind the weekly topic and defining the associated skills required;
A weekly interactive workshop, aimed at applying the skills to solving practical problems and consolidating understanding of the topic; and

Six laboratory exercises throughout the semester, focusing on the learning of laboratory skills, techniques, data analysis and interpretation.

Assessment

1 - Laboratory assessments

2 - In-semester quizzes

3 - Protein analysis

4 - Final assessment - Exam (2 hours and 10 minutes)

Scheduled and non-scheduled teaching activities

Laboratories

Workshops

Workload requirements

Workload

Availability in areas of study

Biochemistry
Microbiology