Handbook

Explain the application of modern genetic techniques such as gene mapping, genome-wide association studies and individual genome-sequencing to: i) the characterisation , diagnosis and treatment of simple and complex human diseases; and ii) the identification of individuals and relationships between individuals by forensic genetics;

Describe how variations in the DNA sequence of a gene can result in changes in gene function that ultimately lead to disease symptoms and explain how improved understanding of this molecular pathology can aid in the treatment of disease, and illustrate the value of model organisms in investigating the molecular pathology of human diseases;

Appraise ethical issues affecting both the individual and society raised by advances in human genetics;

Demonstrate high-level skills in data collection, analysis, interpretation and presentation, and apply these in written scientific reports and oral presentations;

Apply advanced problem-solving skills to issues of medical and forensic genetics;

Critically evaluate and summarise new discoveries from the scientific literature in medical and forensic genetics.